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Symbol Name ID |
Mirc14
microRNA cluster 14, including Mir181a-1 through Mir181b-1 MGI:5313566 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased thymocyte apoptosis |
decreased T cell proliferation |
thymus hypoplasia |
decreased thymocyte number |
decreased DN1 thymic pro-T cell number |
decreased DN3 thymocyte number |
abnormal T cell differentiation |
abnormal T cell receptor V(D)J recombination |
decreased double-positive T cell number |
decreased germinal center B cell number |
increased marginal zone B cell number |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
increased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased NK T cell number |
abnormal NK T cell morphology |
abnormal alpha-beta intraepithelial T cell morphology |
abnormal T cell physiology |
decreased interferon-gamma secretion |
decreased interleukin-13 secretion |
decreased interleukin-4 secretion |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Mirc14tm1.1Ankr/Mirc14tm1.1Ankr | * | |||||||||||||||||||||||
| Mirc14tm1.2Czc/Mirc14tm1.2Czc | ||||||||||||||||||||||||
| Mirc14tm1.2Flv/Mirc14tm1.2Flv | ||||||||||||||||||||||||
| Mirc14tm1.1Czc/Mirc14tm1.1Czc Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+ (conditional) |
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| Mirc14tm1.1Flv/Mirc14tm1.1Flv Tg(Cd4-cre)1Cwi/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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